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3. Karin Bergquist and Linford Detweiller (Over the Rhine)
Quietly crafting one of the best oeuvres in all of American music, the Ohioans at the heart of Over the Rhine have been together as a band since 1989 and as husband and wife since 1996. If you've never heard OtR, stop what you're doing and listen to these two songs, the first because it's timely, the second because it's amazing.


Great list--I'd add Kevin and Anita Robinson of Viva Voce.
No Richard & Linda Thompson? This list lost all credibility.
Loudon Wainwright III & Kate McGarrigle! Neil Young & Pegi Young! J.Lo and Marc Anthony!
Absof***inglutely Jar!
With out the brutal and brilliant darkness duo of R & L Thompson, this list becomes a top 11 without a #1.
Wow, Jar. Usually I just enjoy reading the comments and seeing how people would rank stuff differently than me, but I have to fall on my sword on this one. I even scrolled through every artist on my iPod and somehow zipped right by "Shoot Out the Lights." Let me make this addendum and slot Richard & Linda Thompson at #3. Everybody drops down a spot. Sorry, Richard. Sorry, Linda. Don't know how I forgot ya.
C'mon this list has to include Richard and Linda Thompson, and Brett and Rene Sparks of the Hansome Family.
What about Don & Karen Peris of The Innocence Mission?
Wow, Ike and Tina and Johnny and June are the only ones I've ever heard of.
How about Delaney and Bonnie, Sonny and Cher, Rita and Waylon?
How about Sonic Youth - Kim Gordon and Thurston Moore have amassed a huge and critically acclaimed body of work.