Nora Ephron, who was best known for her work on romantic comedies like When Harry Met Sally and Sleepless in Seattle, died today, according to The Washington Post. She was 71. It was reported that Ephron died from complications of a blood disorder called myelodysplasia, although reports initially didn’t list a cause of death.
Ephron was born in 1941 in New York City. Her first success in Hollywood came after penning the 1983 film Silkwood, which starred Meryl Streep and earned her an Oscar nomination. Other notable films included Heartburn, which was based off Ephron’s novel about her unsuccessful marriage to Watergate reporter Carl Bernstein. Ephron would go on to direct films like You’ve Got Mail and Bewitched. Her final directorial effort was Julie & Julia.
Ephron leaves behind her husband Nicholas Pileggi and sisters Delia and Amy.