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By 2003's Def Jam Vendetta, rapping fighting games had supplemented such Wu Tang members as Method Man with non Wu Tang members like Redman.
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2004's Def Jam: Fight For NY expanded the roster even more, adding Busta Rhymes and other famous rappers.
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Ice-T, David Banner, random white dude, Johnny Mnemonic star Henry Rollins: Def Jam: Fight For NY was a true rap hall of fame.
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In 2009 50 Cent and his G-Unit pals Tony Yayo and Lloyd Banks rescued a $10 million diamond encrusted skull from a terrorist in the shooter 50 Cent: Blood on the Sand.
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Apparently two of these guys are in Incubus? This is an advergame made in 2011 by the marketing arm of a videogame magazine.
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Spice World, the game adaptation of the movie event of 1998, puts you in control of the Spice Girls' live show and videos.
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2011's The Black Eyed Peas Experience is basically a Just Dance game starring one of those fake bands you see in bad teen movies.
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RZA of Wu Tang also shows up in DJ Hero 2.
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The DJ Hero series starred a number of top DJs and electronic artists. Here is a band of friendly robots called "Daft Punk." (?!)
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Also from DJ Hero, here's that appalling abomination of nature, Deadmau5.