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The Arecibo Observatory
Not only does this picture show the scale of humanity's achievements, it also acts an homage to Sagan's previous attempt to send a message to extraterrestrial life. Picture is the Arecibo Observatory, the largest single-dish telescope in the world at the time and the device that beamed Sagan's Arecibo message into space in 1974.
Image via National Astronomy and Ionosphere Center, NASA
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One of the final images on the record, this picture shows Edward H. White during the first spacewalk on June 3, 1965. It honors White and the crew of Apollo 1 who died in a fire in 1967. It also communicates to whoever or whatever may be viewing it that humanity has left Earth's gravity and are exploring space.
Image via NASA