Shameless (1.05)

Lying in a hospital bed, Frank (William Macy) says, “Here’s what you missed on Shameless last week. I got really drunk. (Long pause.) I’m not sure what happened after that.” The 21st Century’s version of a family sitcom continues.
The citizens of Chicago’s projects have an interesting outlook on life in America, especially in The Alibi Room. When Frank is told he needs to have a biopsy taken from his testicles, resulting from the doctor’s concern that Frank has three family jewels even though he’s had them his entire life, Frank begins to worry. But a fellow bar patron reassures him. “Look at Lance Armstrong. He had that ball cancer? Ends up fucking a rock star!” Over dinner, however, Frank believes he’s going to die when Sheila tearfully consoles him, telling him he can have Eddie’s cemetery plot. The biopsy scene with the pretty nurse who shaves him and the chain-smoking, large-needle-bearing, manly grandma doctor is painfully priceless.
Frank sits in on a group therapy session for cancer victims (all women) and gives his two cents on his supposedly cancerous balls. “No underwear that’s been devised to hold them effectively in place, they’re a bizarre appendage.” This is the effectiveness of Frank’s character. His non sequiturs are not simply out of place. They often make sense in the most absurd ways.