Jonathan Lethem Tackles Telepathy and a Tumor in A Gambler’s Anatomy

Is Jonathan Lethem’s latest novel a study in identity and self-perception, hidden beneath the mask of an underworld thriller?
Is it an examination of the brain, mind and consciousness, wrapped in the disguise of a dramatic homecoming story?
Or, rather, is it a discourse on the humanity’s uneasy conflict between anarchy and extreme wealth, cloaked in a reality-warping narrative of telepathic connectivity?
In A Gambler’s Anatomy, Lethem calls on his virtuosic versatility to stitch together an unpredictable and fascinating story, hopping continents, genre and subject matter with ease. At the fore is Alexander Bruno, a high-stakes backgammon hustler who finds himself in Berlin for a match intended to halt a bad luck streak he’d developed in Singapore.
Bruno, however, has been experiencing a growing blot in the center of his vision and falls ill at his wealthy target’s home, suffering a bloody nose and losing unconscious. Scans at the hospital reveal a sizable tumor in his olfactory groove. Is the tumor fatal? Is it operable? Is it even cancer? More importantly to Bruno, could it be the cause of this recent string of bad luck?
Those questions hang unanswered in the hospital’s sterile air as the book backtracks to Singapore and Bruno’s fateful encounter with Keith Stolarsky, an acquaintance from his youth in Berkeley. That tenuous reconnection has already upset Bruno, confronted by the “treacherous intensity of restored memory,” but it also provides his opportunity to return to the San Francisco Bay Area, on Stolarsky’s dime, for an experimental treatment by the one surgeon who could potentially help.
Stolarsky, a rich slob who litters the floor of his Jaguar with food trash, has earned a fortune—and a Darth Vader reputation—as a Berkeley developer and sets Bruno up in an apartment. Bruno’s return to California after 30 years is a culture shock. He understands the Darth Vader reference, but is bewildered at the mention of Hooters and popular shirts picturing a bearded man and the word “abide.”